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TZID:Europe/Paris
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BEGIN:VEVENT
UID:1-420@lptms.universite-paris-saclay.fr
DTSTART:20160613T110000Z
DTEND:20160613T120000Z
DTSTAMP:20160606T101738Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-anne-florence-bitbol/
SUMMARY:Physics-Biology interface seminar: Anne-Florence Bitbol - LPTMS\, s
 alle 201\, 2ème étage\, Bât 100\, Campus d'Orsay - 13 Juin 16 11:00
DESCRIPTION:Inferring interaction partners from protein sequences\nAnne-Flo
 rence Bitbol (Laboratoire Jean Perrin\, UPMC)\nSPECIAL LOCATION (due to re
 novation work at LPS)\nSpecific protein-protein interactions play crucial 
 roles in the stability of multi-protein complexes and in signal transducti
 on. Thus\, mapping these interactions is key to a systems-level understand
 ing of cells. However\, systematic experimental identification of protein 
 interaction partners is still challenging\, while a large and rapidly grow
 ing amount of sequence data is now available. Is it possible to identify w
 hich proteins interact just from their sequences? We propose an approach b
 ased on sequence covariation\, building on methods used with success to pr
 edict the three-dimensional structures of proteins from sequences alone. O
 ur method identifies specific interaction partners with high accuracy amon
 g the members of two ubiquitous prokaryotic protein families\, and paves t
 he way to identifying novel protein-protein interactions directly from seq
 uence data.\n
CATEGORIES:physbio,seminars
LOCATION:LPTMS\, salle 201\, 2ème étage\, Bât 100\, Campus d'Orsay\, 15 
 Rue Georges Clemenceau\, Orsay\, 91405\, France
GEO:48.698185;2.181768
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  Orsay\, 91405\, France;X-APPLE-RADIUS=100;X-TITLE=LPTMS\, salle 201\, 2è
 me étage\, Bât 100\, Campus d'Orsay:geo:48.698185,2.181768
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