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TZID:Europe/Paris
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BEGIN:VEVENT
UID:0-810@lptms.universite-paris-saclay.fr
DTSTART:20220105T110000Z
DTEND:20220105T120000Z
DTSTAMP:20220104T150026Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-antoine-fruleux/
SUMMARY:Physics-Biology interface seminar: Antoine Fruleux - Salle des sém
 inaires du FAST et du LPTMS\, bâtiment Pascal n°530 - 5 Jan 22 11:00
DESCRIPTION:Time persistence as a source of large-scale fluctuations in gro
 wing tissues\nAntoine Fruleux (LPTMS)\n\nDue to the current health situati
 on\, this week's seminar will be held online only:\nhttps://cnrs.zoom.us/j
 /96254507481?pwd=VHd4SzFSUzhXZ2hJOWJ4ajhza2dmdz09\nMeeting ID: 962 5450 74
 81\nPasscode: physbi0\n\n\nIn biological tissues\, the space and time vari
 ations of certain properties appear greatly random. Many recent studies in
 vestigate the impact of this randomness on the development of tissues. Suc
 h studies aim\, for example\, at understanding its role in the self-organi
 zation of tissues or at describing how the cellular responses it induces i
 mpact the developments of organs. To better understand the role played by 
 random fluctuations during morphogenesis\, a first step is to have a bette
 r characterization of their properties. Using theoretical modeling\, we pr
 edicted that the spatial extend of fluctuations is large and results from 
 the combined effects of growth and the fluctuation's time persistence. Thi
 s prediction\, which generally applies to any expending media\, has strong
  consequences when considering biological tissues. It notably implies long
  ranged space correlations\, which tend to give rise to random organ shape
 s\, in contradiction with the observed robustness of many organ shapes. An
  explanation for this apparent paradox may be found in the fine tuning of 
 some of the tissue properties to minimize the heterogeneity of organs\, an
 d we investigated the influence of the tissue's response to the mechanical
  stress on the organ shape. Our model’s predictions prompted us to analy
 ze the spectra of fluctuations in growing tissues\, developing a novel app
 roach that is applicable to geometrically disordered materials. After intr
 oducing the main predictions of the model\, I will present the experimenta
 l evidences supporting them in plant tissues. Finally\, I will express the
  questions raised by our findings.
CATEGORIES:physbio,seminars
LOCATION:Salle des séminaires du FAST et du LPTMS\, bâtiment Pascal n°53
 0\, rue André Riviere\, Orsay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Riviere\, Orsay\
 , 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Salle des séminaires du FAST 
 et du LPTMS\, bâtiment Pascal n°530:geo:0,0
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