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TZID:Europe/Paris
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UID:0-1085@lptms.universite-paris-saclay.fr
DTSTART;TZID=Europe/Paris:20260206T110000
DTEND;TZID=Europe/Paris:20260206T120000
DTSTAMP:20260201T203302Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-arthur-alexandre/
SUMMARY:Physics-Biology Interface seminar: Arthur Alexandre - Moyen Amphi\,
  Building 510\, Université Paris-Saclay Orsay - 6 Fév 26 11:00
DESCRIPTION:From transport in channels to population evolution: how heterog
 eneities shape dynamics\nArthur Alexandre (EPFL &amp\; Swiss Institute of 
 Bioinformatics\, Switzerland)\nIn this seminar\, I will discuss two proble
 ms where effective descriptions capture the essential mechanisms at play: 
 one from hydrodynamics and one from population genetics.\nIn hydrodynamics
 \, Taylor dispersion describes the enhanced spreading of particles in a fl
 uid due to the combined effects of diffusion and flow. We show how this ph
 enomenon can be understood in tortuous\, highly corrugated channels using 
 an effective model that captures the main transport properties\, providing
  insight into flows in porous media.\nIn population genetics\, the gut mic
 robiota presents extensive genetic diversity shaped by its flow-dominated 
 environment. Using a minimal model [2] incorporating flow\, diffusion\, an
 d microbial growth that we extend to non-neutral mutations\, we show how s
 patial structure and advection influence the fixation of beneficial mutant
 s. This illustrates the interplay between flow\, growth\, and spatial hete
 rogeneity in shaping microbial evolution.\n\nAlexandre\, A.\, Guérin\, T.
  &amp\; Dean\, D. S. Effective description of taylor dispersion in strongl
 y corrugated channels. Physical Review E 111\, 064124 (2025).\nLabavić\, 
 D.\, Loverdo\, C. &amp\; Bitbol\, A.-F. Hydrodynamic flow and concentratio
 n gradients in the gut enhance neutral bacterial diversity. Proceedings of
  the National Academy of Sciences 119\, e2108671119 (2022).\n
CATEGORIES:physbio,seminars
LOCATION:Moyen Amphi\, Building 510\, Université Paris-Saclay Orsay\, 15 R
 ue Georges Clemenceau\, orsay\, France
GEO:48.698187;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  orsay\, France;X-APPLE-RADIUS=100;X-TITLE=Moyen Amphi\, Building 510\, Un
 iversité Paris-Saclay Orsay:geo:48.698187,2.181768
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TZID:Europe/Paris
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DTSTART:20251026T020000
TZOFFSETFROM:+0200
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