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UID:1-176@lptms.universite-paris-saclay.fr
DTSTART:20131108T140000Z
DTEND:20131108T150000Z
DTSTAMP:20131030T125154Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-aurelien-bancaud/
SUMMARY:Physics-Biology interface seminar: Aurélien Bancaud - Amphi BLANDI
 N du LPS de la Faculté des Sciences d’Orsay (Bâtiment 510) - 8 Nov 13 
 14:00
DESCRIPTION:Conformation and dynamics of DNA in confined environments: cros
 s-talk between chromosomes in the nucleus and polymers in nanochannels\nAu
 rélien Bancaud (Laboratoire d'analyse et d'architecture des systèmes\, T
 oulouse)\n\nGenome structure and dynamics attacts considerable attention i
 n the biology community to eludicate genome regulation principles\, but al
 so for biological physicists who aim to develop models of DNA in vivo. The
  challenges of this research is conceptual but also economical because of 
 expected impact of DNA sequencing or DNA microarrays technologies in perso
 nalized diagnostics.\nOur research is carried out at the nexus of technolo
 gy and biology and aims to provide a physical description of the genome st
 ructural properties. We will first overview our results on chromosome dyna
 mics in living yeast\, showing the unexpected flexibility of these structu
 res in vivo. We will then focus on new methods for chromosome analysis in 
 vitro based on micro- and nano-fluidics\, and we will finally emphasize th
 at that these two topics are not so unrelated\, given that the physics of 
 DNA confined environment can be used as a common research framework.\n
LOCATION:Amphi BLANDIN du LPS de la Faculté des Sciences d’Orsay (Bâtim
 ent 510)\, 15 Rue Georges Clemenceau\, orsay\, France
GEO:48.698187;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  orsay\, France;X-APPLE-RADIUS=100;X-TITLE=Amphi BLANDIN du LPS de la Facu
 lté des Sciences d’Orsay (Bâtiment 510):geo:48.698187,2.181768
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