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TZID:Europe/Paris
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BEGIN:VEVENT
UID:1-183@lptms.universite-paris-saclay.fr
DTSTART:20131001T140000Z
DTEND:20131001T150000Z
DTSTAMP:20130930T110447Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-daniel-axelrod/
SUMMARY:Physics-Biology interface seminar:  Daniel Axelrod - Amphi BLANDIN 
 du LPS de la Faculté des Sciences d’Orsay (Bâtiment 510) - 1 Oct 13 14
 :00
DESCRIPTION:Molecule motion inside secretory granules before and during exo
 cytosis\nDaniel Axelrod (University of Michigan)\nSPECIAL DATE &amp\; TIME
 \nDespite ~10% of the human genome being comprised of secretory proteins\,
  little is known about the dynamics of proteins inside the secretory granu
 le before and during fusion with the plasma membrane.  This talk presents 
 early results on measuring the diffusion coefficient of two proteins withi
 n that submicroscopic and closed space\, and relates the results to secret
 ion and local membrane deformation rates during the fusion event.  The tec
 hniques used\, TIR-FRAP\, TIR-FCS\, and pol-TIRF have general applicabilit
 y\, and the theory and practice of especially the first two is discussed.\
 n
LOCATION:Amphi BLANDIN du LPS de la Faculté des Sciences d’Orsay (Bâtim
 ent 510)\, 15 Rue Georges Clemenceau\, orsay\, France
GEO:48.698187;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  orsay\, France;X-APPLE-RADIUS=100;X-TITLE=Amphi BLANDIN du LPS de la Facu
 lté des Sciences d’Orsay (Bâtiment 510):geo:48.698187,2.181768
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