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TZID:Europe/Paris
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BEGIN:VEVENT
UID:1-462@lptms.universite-paris-saclay.fr
DTSTART:20161130T110000Z
DTEND:20161130T120000Z
DTSTAMP:20161117T104639Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-david-head/
SUMMARY:Physics-Biology interface seminar: David Head - LPTMS\, salle 201\,
  2ème étage\, Bât 100\, Campus d'Orsay - 30 Nov 16 11:00
DESCRIPTION:High-fidelity computational modelling of biofilms and fibre net
 works\nDavid Head (University of Leeds\, UK)\nNOTE THE NEW LOCATION (due t
 o renovation work at LPS)\nMathematical models of complex systems can help
  develop fundamental insight and accelerate the development of\nnovel mate
 rials and therapeutic treatments\, but the simplifications that must neces
 sarily be made reduce both\nvalidity and predictability\, even for complex
  models that are solved numerically. Here I will describe recent\nresults 
 in two research streams aimed at developing and validating high-fidelity i
 n silico models for biofilms\nand fibre networks\, aiming to reduce the re
 alism gap to experimental systems while maintaining sufficient\nperformanc
 e to permit solution for times and system sizes of interest. The first is 
 a bespoke model for biofilms\nin which mechanical relaxation between cells
  replaces the "pushing" rules typically used\, and has been applied\nto th
 e archetypal biofilm of dental plaque\, revealing insight into long-term e
 cological dynamics not easily\nassayed experimentally. Secondly\, I will d
 iscuss dynamic simulations of peptide gels and collagen hydrogel\nscaffold
 s\, both having important applications as novel biomaterials but where net
 work formation must also be\nsimulated to better approximate the experimen
 ts\; reaching realistic time scales is a substantial challenge.
CATEGORIES:physbio,seminars
LOCATION:LPTMS\, salle 201\, 2ème étage\, Bât 100\, Campus d'Orsay\, 15 
 Rue Georges Clemenceau\, Orsay\, 91405\, France
GEO:48.698185;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  Orsay\, 91405\, France;X-APPLE-RADIUS=100;X-TITLE=LPTMS\, salle 201\, 2è
 me étage\, Bât 100\, Campus d'Orsay:geo:48.698185,2.181768
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