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TZID:Europe/Paris
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BEGIN:VEVENT
UID:0-676@lptms.universite-paris-saclay.fr
DTSTART:20191106T110000Z
DTEND:20191106T120000Z
DTSTAMP:20191027T155153Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-heiko-rieger/
SUMMARY:Physics-Biology interface seminar: Heiko Rieger - Salle des sémina
 ires du FAST et du LPTMS\, bâtiment Pascal n°530 - 6 Nov 19 11:00
DESCRIPTION:Biophysics of Killing – Theory and Experiment\nHeiko Rieger (
 Saarland University)\nCytotoxic T lymphocytes and natural killer cells are
  the main cytotoxic killer cells of the human body to eliminate pathogen-i
 nfected or tumorigenic cells. Various processes are involved in a successf
 ul killing event: activation of the killer cell\, migration and search for
  the target\, formation of a synapse and polarization upon contact with th
 e target\, transport of cytotoxic agents towards the synapse\, and finally
  elimination of the target via necrosis or apoptosis. In this talk I will 
 review various biophysical aspects of killing that were studied in collabo
 ration with experimental groups from biology and medicine. Topics include 
 the analysis of search strategies of migrating killer cells\; the mechanis
 tic understanding of the molecular motor driven cytoskeleton rotation towa
 rds the synapse during polarization\; the efficiency of the spatial organi
 zation of the cytoskeleton for search problems occurring in intra-cellular
  cargo transport\; and the stochastic analysis of different killing strate
 gies via inducing necrosis or apoptosis.\n
CATEGORIES:physbio,seminars
LOCATION:Salle des séminaires du FAST et du LPTMS\, bâtiment Pascal n°53
 0\, rue André Riviere\, Orsay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Riviere\, Orsay\
 , 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Salle des séminaires du FAST 
 et du LPTMS\, bâtiment Pascal n°530:geo:0,0
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