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TZID:Europe/Paris
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UID:0-801@lptms.universite-paris-saclay.fr
DTSTART:20220216T110000Z
DTEND:20220216T120000Z
DTSTAMP:20220211T081748Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-jennifer-mcmanus/
SUMMARY:Physics-Biology interface seminar: Jennifer McManus - Salle des sé
 minaires du FAST et du LPTMS\, bâtiment Pascal n°530 - 16 Fév 22 11:00
DESCRIPTION:Understanding protein phase transitions for globular\, membrane
  and de novo proteins\nJennifer McManus (University of Bristol)\n\nProtein
  phase transitions in biology are associated with disease pathogenesis\, f
 or example in cataract disease or sickle cell anaemia\, but they also occu
 r as part of normal biological processes\, such as liquid-liquid phase sep
 aration in cells. While protein phase behaviour has been understood from a
  physics perspective for globular proteins for some time\, how we can appl
 y what we already know to biomolecular condensation\, or the phase transit
 ions of other protein types is less clear. In my talk\, I’ll briefly rev
 iew what we understand about the phase transitions of globular proteins an
 d then present recent results on the phase behaviour of membrane proteins 
 and the rational design of de novo proteins to undergo liquid-liquid phase
  separation in cells. I’ll highlight what common features exist between 
 these different protein types and how this might be important for biomolec
 ular condensation in cells.\n\nBio\nJennifer McManus completed her BSc and
  PhD degrees in Chemistry at University College Dublin. Following postdoct
 oral appointments at the University of Fribourg in Switzerland and the Mas
 sachusetts Institute of Technology\, she established the Soft Matter and B
 iophysical Chemistry research group at Maynooth University in Ireland as a
  Science Foundation Ireland Stokes Lecturer. She was promoted to Associate
  Professor in 2016 and served as Head of Department between 2017 and 2020.
  She moved to the School of Physics at the University of Bristol in Februa
 ry 2020.
CATEGORIES:physbio,seminars
LOCATION:Salle des séminaires du FAST et du LPTMS\, bâtiment Pascal n°53
 0\, rue André Riviere\, Orsay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Riviere\, Orsay\
 , 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Salle des séminaires du FAST 
 et du LPTMS\, bâtiment Pascal n°530:geo:0,0
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