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TZID:Europe/Paris
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BEGIN:VEVENT
UID:1-240@lptms.universite-paris-saclay.fr
DTSTART:20140328T140000Z
DTEND:20140328T150000Z
DTSTAMP:20140318T070742Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-lukas-kapitein/
SUMMARY:Physics-Biology interface seminar: Lukas Kapitein - Amphi BLANDIN d
 u LPS de la Faculté des Sciences d’Orsay (Bâtiment 510) - 28 Mar 14 14
 :00
DESCRIPTION:Navigating the cytoskeleton: novel tools to dissect and direct 
 intracellular transport\nLukas Kapitein (Universiteit Utrecht\, The Nether
 lands)\nActive transport is important for proper cellular organization and
  functioning. Such transport is driven by a large variety of molecular mot
 or proteins that can walk over cytoskeletal biopolymers such as microtubul
 es and F-actin. Whereas controlled biophysical experiments using purified 
 components have revealed many of the basic properties of these fascinating
  machines\, much less is known about their specific intracellular activity
  and about the interplay between cytoskeletal organization and transport. 
 To address these questions\, we have developed novel tools to control the 
 activity of specific motors inside cells. These experiments have revealed 
 different mechanisms by which the underlying organization of the microtubu
 le network guides motor transport to specific destinations. In addition\, 
 these tools enabled us to remote-control intracellular transport and alter
  cellular behavior using light.\nLukas Kapitein is assistant professor at 
 the Division of Cell Biology of Utrecht University\, where his group devel
 ops novel approaches to understand how the cytoskeleton and their associat
 ed motor proteins contribute to cellular organization and morphology. The 
 combined use of well-controlled\, inducible intracellular transport assays
  and fluorescence nanoscopy of the cytoskeleton offers unique insights int
 o the interplay between cytoskeletal organization and motor-driven transpo
 rt.
LOCATION:Amphi BLANDIN du LPS de la Faculté des Sciences d’Orsay (Bâtim
 ent 510)\, 15 Rue Georges Clemenceau\, orsay\, France
GEO:48.698187;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  orsay\, France;X-APPLE-RADIUS=100;X-TITLE=Amphi BLANDIN du LPS de la Facu
 lté des Sciences d’Orsay (Bâtiment 510):geo:48.698187,2.181768
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