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TZID:Europe/Paris
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BEGIN:VEVENT
UID:1-441@lptms.universite-paris-saclay.fr
DTSTART:20160711T110000Z
DTEND:20160711T120000Z
DTSTAMP:20160708T103204Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-markus-basan/
SUMMARY:Physics-Biology interface seminar: Markus Basan - LPTMS\, salle 201
 \, 2ème étage\, Bât 100\, Campus d'Orsay - 11 Juil 16 11:00
DESCRIPTION:Tradeoffs between fast growth and adaptability shape microbial 
 phenotypes\nMarkus Basan (ETH Zurich\, Switzerland &amp\; Harvard Universi
 ty\, USA)\nSPECIAL LOCATION (due to renovation work at LPS)\n\nMicroorgani
 sms exhibit a striking diversity of phenotypes in different conditions. Ch
 anges in growth rates are accompanied by large variations in metabolic str
 ategies\, gene expression and cell size. However\, the molecular basis and
  underlying rationale of many of these complex patterns remains poorly und
 erstood. We illustrate how a quantitative approach\, based on establishing
  empirical relations between cellular phenotypes\, can help to elucidate s
 uch questions by focusing on three long-standing biological problems: the 
 origin of overflow metabolism\, the control of cell size and finally we pr
 ovide an outlook on the emergence of severe\, multi-hour lag phases. Coars
 e-grained models yield a quantitative and predictive understanding of phen
 otypic patterns under environmental as well as genetic perturbations and c
 an even shed light on underlying molecular mechanisms. A common theme that
  emerges from these seemingly diverse questions is the existence of fundam
 ental tradeoffs between fast growth and the ability to swiftly adapt to en
 vironmental changes or stress conditions.\n
CATEGORIES:physbio,seminars
LOCATION:LPTMS\, salle 201\, 2ème étage\, Bât 100\, Campus d'Orsay\, 15 
 Rue Georges Clemenceau\, Orsay\, 91405\, France
GEO:48.698185;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  Orsay\, 91405\, France;X-APPLE-RADIUS=100;X-TITLE=LPTMS\, salle 201\, 2è
 me étage\, Bât 100\, Campus d'Orsay:geo:48.698185,2.181768
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