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TZID:Europe/Paris
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BEGIN:VEVENT
UID:1-557@lptms.universite-paris-saclay.fr
DTSTART:20180307T110000Z
DTEND:20180307T120000Z
DTSTAMP:20171029T133639Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-pierre-sens/
SUMMARY:Physics-Biology interface seminar: Pierre Sens - Moyen Amphi\, Buil
 ding 510\, Université Paris-Saclay Orsay - 7 Mar 18 11:00
DESCRIPTION:Mechano-sensitive adhesion in cell spreading and crawling\nPier
 re Sens (Institut Curie\, Paris)\n\nCrawling cell motility is powered by a
 ctin polymerization and acto-myosin contraction. When moving over a flat a
 nd rigid substrate\, cells usually develop thin and broad protrusions at t
 heir front\, called lamellipodia\, where actin polymerisation generates a 
 protrusive force pushing the front edge of the cell forward. The lamellipo
 dium displays interesting dynamics\, including normal and lateral waves\, 
 possibly relevant to cell polarisation and the initiation of motion. I wil
 l discuss a stochastic model of mechano-sensitive cell adhesion\, and disc
 uss its relevance for symmetry breaking\, cell polarisation\, and motility
 . I will then discuss a generic model of micro-crawlers\, built as an exte
 nsion of low Reynolds number micro-swimmers\, that highlights the crucial 
 role of mechano-sensitive adhesion for the active crawling of cells and bi
 omimetic objects.\n
CATEGORIES:physbio,seminars
LOCATION:Moyen Amphi\, Building 510\, Université Paris-Saclay Orsay\, 15 R
 ue Georges Clemenceau\, orsay\, France
GEO:48.698187;2.181768
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