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TZID:Europe/Paris
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UID:1-172@lptms.universite-paris-saclay.fr
DTSTART:20130927T134500Z
DTEND:20130927T150000Z
DTSTAMP:20130925T194429Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-i
 nterface-seminar-timo-betz/
SUMMARY:Physics-Biology interface seminar: Timo Betz - Amphi BLANDIN du LPS
  de la Faculté des Sciences d’Orsay (Bâtiment 510) - 27 Sep 13 13:45
DESCRIPTION:The mechanics of active and passive cellular assemblies: How bi
 omimetic reconstitution can help to understand living cell\nTimo Betz (Ins
 titut Curie - Paris)\nUnderstanding the intriguing complexity of living sy
 stems is one of the main driving forces of science. To gain insight we use
  biomimetic systems that reconstitute well defined cellular assemblies and
  compare these to the living system. Our main interests are the mechanical
  properties and the generation of forces\, both mediated by the cytoskelet
 on and its interaction with the plasma membrane. Recent advances allow to 
 mimic structures such as the actin cortex\, sparse actin networks and acti
 n bundles\, and we use optical tweezers to quantify the mechanical propert
 ies of these structures and to compare them to living cells. While sparse 
 actin networks and polymerizing actin bundles show rather passive behavior
 \, we apply the same measurement methods to living cells such as cell bleb
 s and red blood cells which allow to study the out-of-equilibrium mechanic
 s of these systems\, and to determine the timescale at which the system's 
 activity becomes evident.
LOCATION:Amphi BLANDIN du LPS de la Faculté des Sciences d’Orsay (Bâtim
 ent 510)\, 15 Rue Georges Clemenceau\, orsay\, France
GEO:48.698187;2.181768
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  orsay\, France;X-APPLE-RADIUS=100;X-TITLE=Amphi BLANDIN du LPS de la Facu
 lté des Sciences d’Orsay (Bâtiment 510):geo:48.698187,2.181768
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