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TZID:Europe/Paris
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UID:1-159@lptms.universite-paris-saclay.fr
DTSTART:20130717T143000Z
DTEND:20130717T153000Z
DTSTAMP:20130723T101951Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/seminaire-du-lptm
 s-4/
SUMMARY:Séminaire exceptionnel du LPTMS : Adélaïde Raguin - LPTMS\, sall
 e 201\, 2ème étage\, Bât 100\, Campus d'Orsay - 17 Juil 13 14:30
DESCRIPTION:Traffic regulated by junctions: A statistical model motivated b
 y cytoskeletal transport\nAdélaïde Raguin\, Université Montpellier 2\nA
 ctive intracellular transport of motor proteins along the cytoskeleton is 
 an important mechanism essential to accomplish many biological functions i
 n eukaryotic cells. For instance\, motor protein transport is involved in 
 cell migration\, feeding of the cell\, and cell contractions. Importantly\
 , several neurodegenerative diseases are a consequence of the malfunctioni
 ng of motor protein transport.\nMotor protein transport forms as well a ch
 allenge in statistical physics. It consists in the study of a non-equilibr
 ium transport process along a complex and dynamic network. The totally asy
 mmetric simple exclusion process (TASEP) can be considered as a minimal mo
 del to study motor protein transport. Along a single segment this model ha
 s been well studied\, but how active particles organize along a complex ne
 tworks has not been studied extensively. Motivated by recent experimental 
 works based on tracer experiments of motor proteins moving along junctions
  of intersecting cytoskeletal filaments we formulate the TASEP along a jun
 ction. The first part of my talk will deal with how the microscopic traffi
 c dynamics at a junction can modulate the transport on the whole network. 
 In the second part of my talk I will introduce a more realistic model of m
 otor protein transport at the junctions. Using the tools developed earlier
  I can characterize the various stationary states of motors moving along c
 omplex junctions as arising in living cells.
LOCATION:LPTMS\, salle 201\, 2ème étage\, Bât 100\, Campus d'Orsay\, 15 
 Rue Georges Clemenceau\, Orsay\, 91405\, France
GEO:48.698185;2.181768
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  Orsay\, 91405\, France;X-APPLE-RADIUS=100;X-TITLE=LPTMS\, salle 201\, 2è
 me étage\, Bât 100\, Campus d'Orsay:geo:48.698185,2.181768
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