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UID:0-735@lptms.universite-paris-saclay.fr
DTSTART;TZID=Europe/Paris:20201110T110000
DTEND;TZID=Europe/Paris:20201110T110000
DTSTAMP:20201102T100049Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/seminaire-du-lptm
 s-david-zwicker/
SUMMARY:Séminaire du LPTMS : David Zwicker (MPI DS Goettingen) -  - 10 Nov
  20 11:00
DESCRIPTION:Controlling phase separation in biological cells\nDavid Zwicker
  (Max Planck Institute for Dynamics and Self-Organization\, Göttingen)\n\
 nOnline seminar --- Zoom Meeting ID: 944 4358 5604 --- Passcode: 322346 --
 -\n\n\nPhase separation has emerged as an essential concept for the spatia
 l organization inside cells. In particular\, phase separation explains how
  droplets can form spontaneously to create subcellular compartments. Howev
 er\, traditional theories of phase separation cannot explain how cells cou
 ld control these droplets. To unveil part of this mystery\, I will present
  two different mechanisms used by cells in this talk. I will first discuss
  chemical reactions that influence the physical properties of droplet comp
 onents. Driving such reactions by exploiting the non-equilibrium environme
 nt of biological cells can stabilize multiple droplets and control their s
 ize. I will then focus on the elastic properties surrounding droplets\, e.
 g.\, provided by the cytoskeleton. I will show that stiffness gradients\, 
 which are present in heterogeneous environments like cells\, can influence
  the positioning of droplets and thus determine their overall arrangement.
  These two examples demonstrate that heterogeneous\, living cells can regu
 late the size\, number\, and position of their droplets. Moreover\, simila
 r mechanisms may allow controlling droplets in technical applications in t
 he future.\n
CATEGORIES:seminars
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