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UID:0-1031@lptms.universite-paris-saclay.fr
DTSTART;TZID=Europe/Paris:20250429T110000
DTEND;TZID=Europe/Paris:20250429T120000
DTSTAMP:20250414T070751Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/seminaire-du-lptm
 s-greg-grason-u-mass-amherst/
SUMMARY:Séminaire du LPTMS : Greg Grason (U Mass\, Amherst) - Salle des s
 éminaires du FAST et du LPTMS\, bâtiment Pascal n°530 - 29 Avr 25 11:00
DESCRIPTION:Geometrically-programmable assembly of self-limiting material s
 tructures\nGreg Grason (U Mass\, Amherst)\n&nbsp\;\n\nLiving systems make 
 a variety of functional and remarkably adaptive material structures via as
 sembly of highly complex\, nanoscale protein “building blocks”.  Man
 y of these architectures\, from viral capsid shells to multi-filament extr
 acellular protein fibers\, have well-defined and finite sizes\, and moreov
 er\, their functional properties (e.g. transport mediation\, mechanics) re
 ly on specific control of that finite size.  Notably this class “self-
 limiting” assembly is distinct from almost all types of synthetic self-a
 ssembled materials\, which often target well-defined and complex local str
 uctures\, such as crystals\, but exhibit unregulated\, if not unlimited\, 
 dimensions at the large scale.  In this talk\, I discuss recent progress
  in understanding and engineering /self-limiting assemblies/\, in which th
 e equilibrium dimensions of complex material structure are encoded in comp
 lex building blocks from which they assemble.  This is motivated both by
  aspirational examples of finite-size\, functional assemblies in biology\,
  but also new classes of programmable particles that incorporate many key 
 features of protein-like assembly (e.g. lock-and-key type “specific” i
 nteractions and geometrically-defined subunit shapes).   I will discuss
  combined experimental and theoretical studies of a basic mechanism of /se
 lf-closing\, curvature-controlled assembly/ of a range of bioinspired caps
 ules\, tubules and bicontinuous structures\, recently realized via DNA-ori
 gami based colloids.  These reveal basic trade-offs between design econo
 my and size-selectivity of target structures\, and further\, suggest stron
 g symmetry-based rules for minimal-complexity\, high-fidelity assembly in 
 the limit of large self-closing size.
CATEGORIES:seminars
LOCATION:Salle des séminaires du FAST et du LPTMS\, bâtiment Pascal n°53
 0\, rue André Riviere\, Orsay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Riviere\, Orsay\
 , 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Salle des séminaires du FAST 
 et du LPTMS\, bâtiment Pascal n°530:geo:0,0
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DTSTART:20250330T030000
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