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UID:0-828@lptms.universite-paris-saclay.fr
DTSTART;TZID=Europe/Paris:20220607T113000
DTEND;TZID=Europe/Paris:20220607T123000
DTSTAMP:20220527T164120Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/seminaire-du-lptm
 s-joachim-krug-cologne/
SUMMARY:Séminaire du LPTMS : Joachim Krug (Uni Cologne) - Salle des sémin
 aires du FAST et du LPTMS\, bâtiment Pascal n°530 - 7 Juin 22 11:30
DESCRIPTION:Discrete and continuous geometry of fitness landscapes\nJoachim
  Krug (University of Cologne)\nHybrid: onsite seminar + zoom.\n\nhttps://c
 nrs.zoom.us/j/97115217092?pwd=VWRlT3MvV1NIRmlraXZ4Q3BpYzVvZz09\nMeeting ID
 : 971 1521 7092\nPasscode: UKZV8d\n\nDarwinian evolution is driven by rand
 om mutations and selection that favors genotypes with high fitness. Genoty
 pes are commonly represented by bitstrings of length L. An overview of pos
 sible evolutionary trajectories is then provided by the acyclic oriented L
 -cube graph {0\,1}^L with nodes labeled by genotypes and edges directed to
 wards higher fitness. The same formal description applies to energy landsc
 apes of spin systems. Some notion of curvature is necessary for a more com
 plete analysis. For this purpose\, Beerenwinkel\, Pachter and Sturmfels (S
 tatistica Sinice\, 2007) have introduced triangulations of the continuous 
 cube [0\,1]^L that are induced by the landscape. Points in the continuous 
 cube are vectors of allele frequencies\, corresponding to the average magn
 etization of individual spins. The talk focuses on the constraints imposed
  by the triangulations on the geometric pattern of fitness peaks (metastab
 le states)\, and is based on joint work with Kristina Crona\, Daniel Oros 
 and Malvika Srivastava.
CATEGORIES:seminars
LOCATION:Salle des séminaires du FAST et du LPTMS\, bâtiment Pascal n°53
 0\, rue André Riviere\, Orsay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Riviere\, Orsay\
 , 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Salle des séminaires du FAST 
 et du LPTMS\, bâtiment Pascal n°530:geo:0,0
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