BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//wp-events-plugin.com//6.4.7.2//EN
TZID:Europe/Paris
X-WR-TIMEZONE:Europe/Paris
BEGIN:VEVENT
UID:1-283@lptms.universite-paris-saclay.fr
DTSTART:20141118T110000Z
DTEND:20141118T120000Z
DTSTAMP:20141103T123316Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/seminaire-du-lptm
 s-lisa-manning/
SUMMARY:Séminaire du LPTMS: Lisa Manning - LPTMS\, salle 201\, 2ème étag
 e\, Bât 100\, Campus d'Orsay - 18 Nov 14 11:00
DESCRIPTION:Dynamical arrest of cell motion in tissues: a constant-density 
 rigidity transition\nLisa Manning\, Syracuse University\nFor important bio
 logical functions such as wound healing\, embryonic development\, and canc
 er tumorogenesis\, cells must initially rearrange and move over relatively
  large distances\, like a liquid. Subsequently\, these same tissues must u
 ndergo buckling and support shear stresses\, like a solid. Our work sugges
 ts that biological tissues can accommodate these disparate requirements be
 cause the tissues are close to glass or jamming transition. While recent s
 elf propelled particle models generically predict a glass/jamming transiti
 on that is driven by packing density φ and happens at some critical φc &
 lt\; 1\, many confluent biological tissues appear to undergo a jamming tra
 nsition at a constant density (φ = 1). I will discuss a new theoretical f
 ramework for predicting energy barriers and rates of cell migration in 2D 
 tissue monolayers\, and show that this model predicts a novel type of rigi
 dity transition\, which takes place at constant φ = 1 and depends only on
  single cell properties such as cell-cell adhesion\, cortical tension and 
 cell elasticity. I will discuss the implications of these ideas for unders
 tanding cancer tumor boundaries and metastasis and pattern formation durin
 g development.
LOCATION:LPTMS\, salle 201\, 2ème étage\, Bât 100\, Campus d'Orsay\, 15 
 Rue Georges Clemenceau\, Orsay\, 91405\, France
GEO:48.698185;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  Orsay\, 91405\, France;X-APPLE-RADIUS=100;X-TITLE=LPTMS\, salle 201\, 2è
 me étage\, Bât 100\, Campus d'Orsay:geo:48.698185,2.181768
END:VEVENT
END:VCALENDAR