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TZID:Europe/Paris
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UID:0-959@lptms.universite-paris-saclay.fr
DTSTART;TZID=Europe/Paris:20240528T110000
DTEND;TZID=Europe/Paris:20240528T120000
DTSTAMP:20240521T162143Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/seminaire-du-lptm
 s-mehmet-can-ucar-ista-vienna/
SUMMARY:Séminaire du LPTMS : Mehmet Can Uçar (ISTA\, Austria) - Salle des
  séminaires du FAST et du LPTMS\, bâtiment Pascal n°530 - 28 Mai 24 11:
 00
DESCRIPTION:\nSelf-organized versus controlled guidance of cells and tissue
 s\nMehmet Can Uçar (ISTA\, Austria)\nIn living organisms\, coordinated ce
 ll and tissue movement is crucial for processes like morphogenesis\, immun
 e response\, and cancer invasion. While it is commonly assumed that collec
 tive motion is steered by global\, pre-patterned chemical or mechanical cu
 es\, limited evidence supports such long-range guidance in living organism
 s. In contrast\, recent findings are unveiling the prominence of local\, s
 elf-generated cues across different systems\, prompting a shift towards in
 vestigating controlled vs. self-organized guidance. In this talk I will fo
 cus on two distinct systems to explore their guidance principles: (i) The 
 development of branched structures\, such as neurons and lymphatic network
 s\, and (ii) collective migration of immune cells. I will introduce theore
 tical models to predict quantitative signatures of self-organized vs. cont
 rolled guidance\, which I will compare with experimental data at both scal
 es. Finally\, I will discuss the potential of self-organized guidance as a
  robust mechanism to navigate heterogeneous cell populations\, and conclud
 e with some perspectives to link cell- and tissue-scale guidance strategie
 s.\n\n
CATEGORIES:seminars
LOCATION:Salle des séminaires du FAST et du LPTMS\, bâtiment Pascal n°53
 0\, rue André Riviere\, Orsay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Riviere\, Orsay\
 , 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Salle des séminaires du FAST 
 et du LPTMS\, bâtiment Pascal n°530:geo:0,0
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DTSTART:20240331T030000
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TZOFFSETTO:+0200
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