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UID:0-766@lptms.universite-paris-saclay.fr
DTSTART;TZID=Europe/Paris:20210330T110000
DTEND;TZID=Europe/Paris:20210330T120000
DTSTAMP:20210319T140244Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/seminaire-du-lptm
 s-mert-terzi-lptms/
SUMMARY:Séminaire du LPTMS : Mert Terzi (LPTMS) - LPTMS (100% online semin
 ar) - 30 Mar 21 11:00
DESCRIPTION:Collective deformation modes promote fibrous self-assembly in p
 rotein-like particles\nMert Terzi (LPTMS)\n\nOnline seminar --- ZOOM Meeti
 ng ID: 996 6280 8820 -- Password: ask L. Mazza and D. Petrov --\n\nSelf-as
 sembly is a crucial and ubiquitous process for biological systems\, in whi
 ch the building blocks spontaneously organize into larger complexes. If th
 e building blocks fit each other\, self-assembly leads to space filling ag
 gregates. However\, in the case of misfitting particles\, the resulting ag
 gregates may have limiting sizes. When the misfitting particles are deform
 able\, elastic energy builds up during the assembly. The energy cost of el
 astic deformation competes with a surface tension which drives the particl
 es into assembly. In the regime in which these two energies are comparable
 \, particles can assemble into self-limiting structures. The relationship 
 between characteristics of the individual particles and the resulting aggr
 egates is not well understood. Through numerical simulations and elastic c
 oarse-graining we show that this relationship is dominated by collective a
 ggregate deformation modes in a broad class of soft particles. We identify
  two characteristics of particles predictive of the overall aggregate stru
 cture. When individual particles have soft deformation modes\, these modes
  collectively control the size of self-limiting aggregates and lead to lar
 ge-scale structures. The second characteristics is incompressibility which
  favors anisotropic\, and hence fibrous aggregates. Finally\, we discuss t
 he implications of our results to fiber formation in protein aggregation. 
 \n\n
CATEGORIES:seminars
LOCATION:LPTMS (100% online seminar)\, LPTMS - Bâtiment Pascal n° 530 rue
  André Rivière - Université Paris-Saclay\, Orsay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=LPTMS - Bâtiment Pascal n
 ° 530 rue André Rivière - Université Paris-Saclay\, Orsay\, 91405\, Fr
 ance;X-APPLE-RADIUS=100;X-TITLE=LPTMS (100% online seminar):geo:0,0
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DTSTART:20210328T030000
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