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UID:0-777@lptms.universite-paris-saclay.fr
DTSTART:20211004T133000Z
DTEND:20211004T173000Z
DTSTAMP:20210930T130136Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/soutenance-de-the
 se-hugo-le-roy/
SUMMARY:Soutenance de thèse : Hugo Le Roy - Petit amphi\, bâtiment Pascal
  n° 530 - 4 Oct 21 13:30
DESCRIPTION:Elasticity of self assembling bio-materials\npar\n\nHugo Le Roy
 \nHybrid PhD defense: onsite + zoom (https://cnrs.zoom.us/j/95416861091?pw
 d=NlhHOW9BWXM2aDN4UmJSSktpYTZmQT09  Meeting ID: 954 1686 1091 - For pwd\,
  please contact martin.lenz@universite-paris-saclay.fr)\nSelf organization
  is crucial for the wealth of living systems\, both at the molecular and c
 ellular level. To correctly achieve their role a tight control over the sh
 ape and structure of protein for instance\, is required. Any mistake can l
 ead to various disease like Alzheimer\, where proteins aggregate into fibr
 ous structures. On a larger scale\, cells need to probe the mechanical res
 ponse of their environment -the extra cellular matrix- and to adapt their 
 own rigidity to collectively orientate. In this thesis\, we are looking a 
 two different models. In the first part\, we study protein aggregation bey
 ond the microscopical details. By considering elastic assembling particles
 \, we are able to derive generic law and understand the very persistent fo
 rmation of fibers. In the second part\, we model the dynamical response of
  a fashionable class of hydrogels for their bio-compatibility. Material en
 gineers are now able to synthesize materials with more and more subtle beh
 avior\, although understanding certain emergent properties -such as non-ex
 ponential relaxation- can be a major challenge. We design a simple model f
 or the dynamical response of hydrogels connected by large multivalent cros
 slinkers. We are able to account for experimental results\,and rationalize
  their origin.\nJury :\n\nThibaut Divoux\, Laboratoire de Physique ENS Lyo
 n\, examinateur\n\nGreg Grason\, Univ. of Massachusetts Amherst\, rapporte
 ur\n\nMartin Lenz\, LPTMS\, directeur de thèse\n\nEmmanuel Trizac\, LPTMS
 \, examinateur\n\nEmanuela Zaccarelli\, Univ. La Sapienza\, rapportrice\n\
 nZorana Zeravcic\, Laboratoire Gulliver ESPCI\, examinatrice
CATEGORIES:seminars
LOCATION:Petit amphi\, bâtiment Pascal n° 530\, rue André Rivière\, Ors
 ay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Rivière\, Orsay
 \, 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Petit amphi\, bâtiment Pasca
 l n° 530:geo:0,0
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