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BEGIN:VEVENT
UID:0-873@lptms.universite-paris-saclay.fr
DTSTART:20230710T140000Z
DTEND:20230710T140000Z
DTSTAMP:20230623T073658Z
URL:http://www.lptms.universite-paris-saclay.fr/seminars/soutenance-de-the
 se-lara-koehler/
SUMMARY:Soutenance de thèse : Lara Koehler - Petit amphi\, bâtiment Pasca
 l n° 530 - 10 Juil 23 14:00
DESCRIPTION:Principles of self-assembly for particles with simple geometrie
 s and complex interactions\n&nbsp\;\nLara Koehler (LPTMS)\n&nbsp\;\n\nIn l
 iving cells\, proteins self-assemble into large-scale functional structure
 s based both on the specific interactions between different spots on their
  surfaces. The general principles that allow complex interactions to cont
 rol self-assembly are largely unknown. Here\, we introduce model lattice p
 articles with trivial geometries but highly complex interactions and stud
 y their self-assembly using numerical simulations. We find that strongly a
 nisotropic particles produce non-trivial aggregates that fall into a few s
 tereotypical categories. Using machine learning\, we accurately predict th
 e outcome of this aggregation based on the presence of pair interactions t
 hat locally favor periodic un-frustrated arrangements. We also show that 
 the stereotypical aggregates are fixed-points of a numerical real-space re
 normalization transformation.These results offer a first overview of the r
 ich design space associated with identical particles with complex interact
 ions\, and could inspire engineered self-assembling nano-objects as well a
 s help understand the emergence of robust functional protein structures. 
 In particular\, we show that local interaction can robustly control the s
 ize of spherical or fibrous self-assemblies of identical particle. Finall
 y\, we suggest that it is possible to systematically identify the con\n\n&
 nbsp\;\n\nJury : Martin Lenz (directeur de thèse)\, Mikhail Brenner (rapp
 orteur)\, Ralf Evenaers (rapporteur)\, Friedrich Simmel (examinateur)\, Zo
 rana Zeravcic (examinatrice)\, Chase Broederz (examinateur)
CATEGORIES:seminars
LOCATION:Petit amphi\, bâtiment Pascal n° 530\, rue André Rivière\, Ors
 ay\, 91405\, France
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=rue André Rivière\, Orsay
 \, 91405\, France;X-APPLE-RADIUS=100;X-TITLE=Petit amphi\, bâtiment Pasca
 l n° 530:geo:0,0
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