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TZID:Europe/Paris
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BEGIN:VEVENT
UID:1-157@lptms.universite-paris-saclay.fr
DTSTART:20130710T150000Z
DTEND:20130710T160000Z
DTSTAMP:20130706T052951Z
URL:https://www.lptms.universite-paris-saclay.fr/seminars/physics-biology-
 interface-seminar-christoph-cremer/
SUMMARY:Physics-Biology interface seminar : Christoph Cremer - Amphi BLANDI
 N du LPS de la Faculté des Sciences d’Orsay (Bâtiment 510) - 10 Juil 1
 3 15:00
DESCRIPTION:Fluorescence Microscopy of Biostructures @ Molecular Optical Re
 solution\nChristoph Cremer (Institute of Molecular Biology (IMB)\, Mainz\;
  Kirchhoff-Institute for Physics (KIP) and Institute for Pharmacy and Mole
 cular Biotechnology (IPMB)\, University Heidelberg )\nSPECIAL DATE &amp\; 
 TIME Seminar hosted by Olivier Acher &amp\; Guillaume Dupuis\nConventional
  epifluorescence microscopy is limited in resolution (to about 200 nm late
 rally\, 600 nm axially) by the shere nature of light (by diffraction)\, an
 d is hence insufficient to study the nanostructure of subcellular componen
 ts.\nAt IMB-Mainz and Heidelberg University we have established a variety 
 of superresolution microscopy ("nanoscopy") methods\, for example Structur
 ed Illumination SMI and Localisation microscopy SPDMphmyd with blinking dy
 es\, like standard GFP. Our microscope systems can and have been applied t
 o study the composition\, function and metabolism of many biomolecular str
 uctures and small paticles like single viruses in high densities. Currentl
 y we reach a resolution down to 5 nm in 2D and 40 nm in 3D in the co-local
 ization mode.\nThere are various applications in the fields of molecular b
 iology\, (clinical) medicine\, diagnosis and pathology.\n\nChristoph Creme
 r\, Barry R. Masters (2013) Resolution enhancement techniques in microscop
 y\, The European Physical Journal H 38\, 3\, pp 281-344\nKaufmann R\, Mull
 er P\, Hausmann M and Cremer C (2011). Imaging label-free intracellular st
 ructures by localisation microscopy. Micron\, 42\, 348-352.\nKaufmann R\, 
 Müller P\, Hildenbrand G\, Hausmann M and Cremer C (2011) Analysis of Her
 2/neu membrane protein clusters in different types of breast cancer cells 
 using localization microscopy. Journal of Microscopy\, 242\, 46-54.\nGunke
 l M\, Erdel F\, Rippe K\, Lemmer P\, Kaufmann R\, Hoermann C\, Amberger R 
 and Cremer C (2009). Dual color localization microscopy of cellular nanost
 ructures. Biotechnology Journal\, 4\, 927-938.\n\n
LOCATION:Amphi BLANDIN du LPS de la Faculté des Sciences d’Orsay (Bâtim
 ent 510)\, 15 Rue Georges Clemenceau\, orsay\, France
GEO:48.698187;2.181768
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=15 Rue Georges Clemenceau\,
  orsay\, France;X-APPLE-RADIUS=100;X-TITLE=Amphi BLANDIN du LPS de la Facu
 lté des Sciences d’Orsay (Bâtiment 510):geo:48.698187,2.181768
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