Fluctuation Relations and Fitness in Cell Populations
Luca Peliti (Santa Marinella Research Institute)
Hybrid: onsite seminar + zoom.
https://cnrs.zoom.us/j/96871767341?pwd=QngzWUd6cDV2K1R4UUpkNTB0UFkwUT09
Meeting ID: 968 7176 7341
Passcode: 6Wm4Fm
Recent advances in single-cell lapse microscopy allow to monitor the division dynamics and the phenotypic state in growing cell populations. The resulting data allow to infer the fitness of a phenotype in constant and varying environments, by exploiting fluctuation relations similar to those of stochastic thermodynamics. I shall summarize these techniques, highlighting their strong points and possible pitfalls.
Joint work with Arthur Genthon and David Lacoste (ESPCI) and Takeshi Nozoe (Tokyo)