Fluctuation Relations and Fitness in Cell Populations
Luca Peliti (Santa Marinella Research Institute)
Hybrid: onsite seminar + zoom.
Meeting ID: 968 7176 7341
Recent advances in single-cell lapse microscopy allow to monitor the division dynamics and the phenotypic state in growing cell populations. The resulting data allow to infer the fitness of a phenotype in constant and varying environments, by exploiting fluctuation relations similar to those of stochastic thermodynamics. I shall summarize these techniques, highlighting their strong points and possible pitfalls.
Joint work with Arthur Genthon and David Lacoste (ESPCI) and Takeshi Nozoe (Tokyo)