Collective cell motion and statistical mechanics : global modes and fluctuations in confined cell assemblies.
Vincent Hakim (Laboratoire de Physique Statistique, ENS, Paris)
In different biological processes, cells move in a coordinated way. Several experiments have quantitatively investigated this phenomenon. I will describe experimental results obtained by the team of P Silberzan (Institut Curie, Paris) as well as a simple model of interacting persistent random walkers that we have developed to phenomenologically describe collective cell motion. The model helps to explain the observed dynamics of a confined cell assembly which displays stochastic reversals of global rotational motion and pulsatile collective modes.